Childhood Infection and Endothelial Dysfunction

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Endothelial dysfunction in childhood infection.

BACKGROUND Atherosclerosis begins in early life, and endothelial dysfunction is recognized as a key initiating event in the development of atherosclerosis. Although infection has been implicated in endothelial dysfunction and atherogenesis, the impact of acute common childhood infections on the vascular endothelium is unknown. METHODS AND RESULTS We studied 600 children aged 10 years drawn fr...

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A therosclerosis is a chronic vascular inflammatory disease, characterised by lipid accumulation, and cellular infiltration and proliferation in the arterial wall. Vascular endothelial dysfunction plays a critical role in the initiation and progression of the atherosclerotic process; the development of techniques that allow detection of endothelial function and early structural vascular disease...

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Infection, endothelial dysfunction, and atherogenesis.

and Atherogenesis To the Editor: Khairy et al1 reported a lack of association between chronic infection and endothelial function in healthy young men. The study population was highly selective and, excluded women, individuals aged 45 years, and subjects with any conventional risk factors of coronary artery disease (CAD). The authors assumed that serum antibodies against the various infectious a...

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Assessment of Endothelial Dysfunction in Childhood Obesity and Clinical Use

The association of obesity with noncommunicable diseases, such as cardiovascular complications and diabetes, is considered a major threat to the management of health care worldwide. Epidemiological findings show that childhood obesity is rapidly rising in Western society, as well as in developing countries. This pandemic is not without consequences and can affect the risk of future cardiovascul...

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Vasculitis: Endothelial Dysfunction During Rickettsial Infection

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ژورنال

عنوان ژورنال: Circulation

سال: 2005

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.0000161816.52136.66